Full Publication Index for Paul Campagnola is on PubMed and Web of Science at

Highlighted Recent Publications:

G. Hall, K. Tilbury, K.R. Campbell, K.W. Eliceiri, and P.J. Campagnola, “Experimental and simulation study of the wavelength dependent second harmonic generation of collagen in scattering tissues,” Optics Letters, 39(7): 1897-1900 (2014).

K. Tilbury, C.-H. Lien, S.J. Chen and P.J. Campagnola, “Differentiation of Col I and Col III isoforms in stromal models of ovarian cancer by analysis of Second Harmonic Generation polarization and emission directionality,” Biophy. J., 106(2): 354-65 (2014).

G. Hall, K.W. Eliceiri and P.J. Campagnola, “Simultaneous determination of the Second Harmonic Generation emission directionality and reduced scattering coefficient from 3D imaging of thick tissues,” J. Biomed. Optics, 18(11):116008 (2013).

C.-H Lien, K. Tilbury, S.-J. Chen, and P. J. Campagnola, “Precise, motion-free polarization control in Second Harmonic Generation microscopy using a liquid crystal modulator in the infinity space”, Biomed. Optics Express, 4(10) 1991-2002 (2013).

Y. C. Li, C.Y. Chang, C. Y. Lin, N.S Chang, P.J. Campagnola, C.Y. Dong, and S.J. Chen. “High-throughput fabrication of gray-level biomicrostructures via temporal focusing excitation and laser pulse control,” J. Biomed. Optics, 18, 075004 (2013).

V. Ajeti, C.-H. Lien, S.-J. Chen, P.-J. Su, J. M. Squirrell, K. H. Molinarolo, G. E. Lyons, K. W. Eliceiri, B. M. Ogle, and P. J. Campagnola, “Image-inspired 3D multiphoton excited fabrication of extracellular matrix structures by modulated raster scanning,” Optics Express, 21(21), 25346-55 (2013).

L. M. Reusch, K. W. Eliceiri, L. C. Carlson, J. A. Anderson, G. Hall, P. J. Campagnola, T. J. Hall, and H. Feltovich, “Second Harmonic Generation Microscopy and Ultrasound Imaging of Human Cervical Structure,” J. Biomed. Optics, 18, 031110 (2013).

K. P. Hanson, J. P. Jung, Q. A. Tran, S.-P. Hsu; R. Iida, V. Ajeti, P. J. Campagnola, K. W. Eliceiri, J. M. Squirrell, G. E. Lyons, and B. M. Ogle, “Spatial and Temporal Analysis of Extracellular Matrix Proteins in the Developing Murine Heart: A Blueprint for Regeneration,” Tissue Engineering Part A, 19, 1132-1143 (2013).

X. Chen, Y.-D. Su, V. Ajeti, S.-J. Chen, and P.J. Campagnola, “Cell adhesion on micro-structured fibronectin gradients fabricated by multiphoton excited photochemistry,” Cell Mol. Bioeng., 5(3): 307-319 (2012).

Y.-C. Li, L.-C. Cheng, C.-Y Chang, C.-H. Lien, P. J. Campagnola and S.-J. Chen, “Fast multiphoton microfabrication of freeform polymer microstructures by spatiotemporal focusing and patterned excitation,” Optics Express, 20, 19030-8 (2012).

G. Hall, K. Eliceiri, and PJ. Campagnola, “Goniometric measurements of thick tissue using Monte Carlo simulations to obtain the single scattering anisotropy coefficient,” Biomed. Optics Ex, 3, 2707-2719 (2012).

Y.-C. Li, L.-C. Cheng, C.-Y Chang, C.-H. Lien, P. J. Campagnola, and S.-J. Chen, “Fast multiphoton microfabrication of freeform polymer microstructures by spatiotemporal focusing and patterned excitation,” Optics Express, 20, 19030-8 (2012).

X. Chen and P.J. Campagnola, “Circular Dichroism Second Harmonic Generation investigations of the connective tissue disorder Osteogenesis imperfecta,” Optics Letters, 37, 3837-3839 (2012).

P.-J. Su, Q. A. Tran, J. J. Fong,  K. W. Eliceiri, B. M. Ogle, and P.J. Campagnola, “Mesenchymal stem cell interactions with 3D ECM modules fabricated via multiphoton excited photochemistry,” Biomacromolecules, 13, 2917-2925 (2012).

X. Chen, S. Plotnikov, O. Nadiarnykh, and P.J. Campagnola “Second Harmonic Generation Microscopy for quantitative analysis of collagen fibrillar structure,” Nature Protocols, 7, 654-669 (2012).

P.J. Campagnola, “Second Harmonic Generation imaging microscopy: Applications to Disease Diagnostics,” Anal. Chem. 83, 3224-3231 (2011).

O. Nadiarnykh, R.B. LaComb, M.A. Brewer, and P. J. Campagnola, “Alterations of the extracellular matrix in ovarian cancer studied by Second Harmonic Generation imaging microscopy,” BMC Cancer 10(1), 94 (2010).

X. Chen, M.A. Brewer, C. Zou and P.J. Campagnola, “Migration and adhesion of ovarian cancer cells on crosslinked laminin fibers nanofabricated by multiphoton excited photochemistry,” Integrative Biology, 1, 469–476 (2009).

O. Nadiarnykh and P. J. Campagnola, “Retention of polarization signatures in SHG microscopy of scattering tissues through optical clearing,” Optics Express, 17, 5794-5806 (2009).

R. Samatham, S. L. Jacques, and P.J. Campagnola, “Optical Properties of Mutant vs Wildtype Mouse Skin Measured by Reflectance-mode Confocal Scanning Laser Microscopy (rCSLM),” J. Biomed. Opt. 13, 041309 (2008).

S. V. Plotnikov, A. Kenny, S. Walsh, B. Zubrowski, C. Joseph, V. L. Scranton, G. A. Kuchel, D. Dauser, M. Xu, C. Pilbeam, D. Adams, R. Dougherty, P. J. Campagnola, and W. A. Mohler, “Measurement of muscle disease by quantitative second-harmonic generation imaging,” J. Biomed. Opt. 13, 044018 (2008).

R. LaComb, O. Nadiarnykh, S. Carey and P.J. Campagnola, “Quantitative SHG imaging and modeling of the optical clearing mechanism in striated muscle and tendon,” J. Biomed. Opt. 13, 021108 (2008).

R. LaComb, O. Nadiarnykh, and P.J. Campagnola, “Second Harmonic Generation imaging of osteogenesis imperfecta: experiment and simulation,” Biophys. J., 94, 4504-4514 (2008).

R. LaComb, O. Nadiarnykh, S. Townsend, and P.J. Campagnola, “Phase Matching considerations in Second Harmonic Generation from tissues: Effects on emission directionality, conversion efficiency and observed morphology,” Optics Comm., 281, 1823-1832 (2008).